The effect of maternal protein restriction during perinatal life on the inflammatory response in pediatric rats

Fetal growth restriction can affect health outcomes in postnatal life. This study tested the hypothesis that response to an inflammatory pulmonary insult is altered pediatric fetal restricted rats. Using a low-protein diet during gestation and life, growth-restricted male female rats healthy control were exposed via intratracheal instillation of heat-killed bacteria. After 6 h, animal lungs examined for lung inflammation status surfactant system. The results showed insult, neutrophil infiltration was decreased both animals compared with amount increased rats, regardless insult. It concluded responses following